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Nitric oxide is a vasodilator, which means that it relaxes and opens the blood vessels to promote better blood flow to your muscles. Better blood flow promotes muscle development because your muscles are getting more of the nutrients they need, faster. That's how supplements, such as Nitric Oxide Boost by Fitness Labs or NO-Xplode by BSN, promote muscle-building and also help with recovery after tough workouts or competitions.
The term “perpetual pump” in bodybuilding circles refers to the ability to maintain a rock-hard muscular appearance all the time, not just immediately after a workout. Some evidence suggests that nitric oxide supplements may contribute toward a more muscular appearance by maintaining the increased blood flow to the muscles even when you're not working out. Generally, an enhanced muscle pump lasts several hours after a workout.
Not all nitric oxide workout formulas are alike, so you may need to try a few to determine what works best for you. Most of these supplements contain a combination of various amino acids such asarginine, L-citrulline and L-norvaline. Some contain creatine, and some contain caffeine. But consult your doctor if you are being treated for either high blood pressure or low blood pressure, because nitric oxide might interact with blood pressure medications.